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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Adenomatous polyposis coli protein' and Ligand = 'BDBM270471'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (Human))
BDBM270471
PNG
(US10071086, Compound 22)
Show SMILES CN(C)Cc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cc(F)cc(CNS(C)(=O)=O)c3)c2c1
Show InChI InChI=1S/C28H24FN9O2S/c1-38(2)15-17-5-19(11-30-9-17)20-8-22-26(36-37-27(22)32-12-20)28-34-24-14-31-13-23(25(24)35-28)18-4-16(6-21(29)7-18)10-33-41(3,39)40/h4-9,11-14,33H,10,15H2,1-3H3/b28-26+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair