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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Adrenergic receptor alpha-1' and Ligand = 'BDBM50291347'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-1


(Homo sapiens (Human))
BDBM50291347
PNG
(CHEMBL164330 | Piperidin-1-yl-[3-(3,4,10,10a-tetra...)
Show SMILES O=C(N1CCCCC1)c1cccc(CN2CCN3C(COc4ccccc34)C2)c1
Show InChI InChI=1/C24H29N3O2/c28-24(26-11-4-1-5-12-26)20-8-6-7-19(15-20)16-25-13-14-27-21(17-25)18-29-23-10-3-2-9-22(23)27/h2-3,6-10,15,21H,1,4-5,11-14,16-18H2
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
200n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was measured in vivo for its binding affinity at Alpha-1 adrenergic receptor using [3H]prazosin as radioligand.


Bioorg Med Chem Lett 7: 763-768 (1997)


Article DOI: 10.1016/S0960-894X(97)00074-7
BindingDB Entry DOI: 10.7270/Q2FT8M1V
More data for this
Ligand-Target Pair