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Found 3 Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, tissue-nonspecific isozyme' and Ligand = 'BDBM409776'
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409776(US10370333, Example I-7)
Affinity DataIC50:  550nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409776(US10370333, Example I-7)
Affinity DataIC50:  876nMAssay Description:Inhibition of TNAP (unknown origin) using PPi as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409776(US10370333, Example I-7)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of TNAP (unknown origin) in whole blood using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed