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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM309293'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))
BDBM309293
PNG
(Trans-N-[2-chloro-4-(trifluoromethyl)benzyl]-4-(3-...)
Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ncccc1F
Show InChI InChI=1S/C20H19ClF4N6O2S/c1-30-11-18(28-29-30)34(32,33)31-9-14(19-16(22)3-2-6-26-19)17(10-31)27-8-12-4-5-13(7-15(12)21)20(23,24)25/h2-7,11,14,17,27H,8-10H2,1H3/t14-,17-/m1/s1
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PC sid
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Article
US Patent
<10n/an/an/an/an/an/an/an/a



AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG

US Patent


Assay Description
Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...


US Patent US9656955 (2017)


Article DOI: 10.1021/jm050458h
BindingDB Entry DOI: 10.7270/Q2Z60R48
More data for this
Ligand-Target Pair