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Found 6 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] A' and Ligand = 'BDBM256686'
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256686(US10053456, 65 | US10414761, Example 65 | US109682...)
Affinity DataIC50:  2.50E+4nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256686(US10053456, 65 | US10414761, Example 65 | US109682...)
Affinity DataIC50:  2.50E+4nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256686(US10053456, 65 | US10414761, Example 65 | US109682...)
Affinity DataIC50:  2.50E+4nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256686(US10053456, 65 | US10414761, Example 65 | US109682...)
Affinity DataIC50:  2.50E+4nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256686(US10053456, 65 | US10414761, Example 65 | US109682...)
Affinity DataIC50:  2.50E+4nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256686(US10053456, 65 | US10414761, Example 65 | US109682...)
Affinity DataIC50:  2.50E+4nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent