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Found 6 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] B' and Ligand = 'BDBM243418'
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM243418(5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM243418(5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM243418(5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM243418(5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- ...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM243418(5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- ...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-B: The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM243418(5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent