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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Androgen receptor (AR)' and Ligand = 'BDBM245175'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen receptor (AR)


(Homo sapiens (Human))
BDBM245175
PNG
(US9428460, 31)
Show SMILES O=C(NC[C@H]1CC[C@@H](CC1)Oc1ccnc2c(cccc12)C#N)c1ccon1
Show InChI InChI=1S/C21H20N4O3/c22-12-15-2-1-3-17-19(8-10-23-20(15)17)28-16-6-4-14(5-7-16)13-24-21(26)18-9-11-27-25-18/h1-3,8-11,14,16H,4-7,13H2,(H,24,26)/t14-,16-
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 720n/an/an/an/an/a37



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
For determining the androgen receptor-dependent transcription, a cellular assay system was used, consisting of PC-3 cells (Kaighn et al., Invest. Uro...


US Patent US9428460 (2016)


BindingDB Entry DOI: 10.7270/Q25719Z7
More data for this
Ligand-Target Pair