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Found 2 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM156378'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM156378(US9018381, 3 | US9248140, 3)
Affinity DataIC50: <0.300nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM156378(US9018381, 3 | US9248140, 3)
Affinity DataIC50:  3.90nMAssay Description:Displacement of synthetic peptide tracer conjugated to fluorescein isothiocyanate from C-terminal 6xHis-tagged Bcl-2 (1 to 204 residues) (unknown ori...More data for this Ligand-Target Pair
In DepthDetails PubMed