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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase' and Ligand = 'BDBM50000852'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50000852
PNG
(4-Methoxy-4-[3-(naphthalen-2-ylmethoxy)-phenyl]-ox...)
Show SMILES COC1(CCCOCC1)c1cccc(OCc2ccc3ccccc3c2)c1
Show InChI InChI=1S/C24H26O3/c1-25-24(12-5-14-26-15-13-24)22-8-4-9-23(17-22)27-18-19-10-11-20-6-2-3-7-21(20)16-19/h2-4,6-11,16-17H,5,12-15,18H2,1H3
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Article
PubMed
n/an/a 200n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenase


J Med Chem 35: 2600-9 (1992)


Article DOI: 10.1021/jm00092a010
BindingDB Entry DOI: 10.7270/Q2Q240VJ
More data for this
Ligand-Target Pair