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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase' and Ligand = 'BDBM50085229'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50085229
PNG
(CHEMBL159516 | {3-Methyl-3-phenyl-1-[4-(quinolin-2...)
Show SMILES CC(C)(CC(O\N=C\C(O)=O)c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccccc1
Show InChI InChI=1S/C29H28N2O4/c1-29(2,23-9-4-3-5-10-23)18-27(35-30-19-28(32)33)22-13-16-25(17-14-22)34-20-24-15-12-21-8-6-7-11-26(21)31-24/h3-17,19,27H,18,20H2,1-2H3,(H,32,33)/b30-19+
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Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay


J Med Chem 43: 690-705 (2000)


Article DOI: 10.1021/jm9904102
BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair