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Found 3 Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM290374'
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290374((2R,3S)-3-amino-2-(3-boronopropyl)pyrrolidine-3-ca...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290374((2R,3S)-3-amino-2-(3-boronopropyl)pyrrolidine-3-ca...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290374((2R,3S)-3-amino-2-(3-boronopropyl)pyrrolidine-3-ca...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent