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Found 4 Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM290393'
TargetArginase-1(Homo sapiens (Human))
New England Discovery Partners

Curated by ChEMBL
LigandPNGBDBM290393((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyridin-2- y...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant arginase 1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in urea production using L-arginine as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
New England Discovery Partners

Curated by ChEMBL
LigandPNGBDBM290393((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyridin-2- y...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
New England Discovery Partners

Curated by ChEMBL
LigandPNGBDBM290393((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyridin-2- y...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
New England Discovery Partners

Curated by ChEMBL
LigandPNGBDBM290393((3R,4S)-3-amino-4-(3-boronopropyl)-1-(pyridin-2- y...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent