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Found 3 Enz. Inhib. hit(s) with Target = 'Aryl hydrocarbon receptor' and Ligand = 'BDBM50049057'
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049057(CHEMBL3319505 | US10730833, Compound 10d | US99696...)
Affinity DataEC50:  86nMAssay Description:Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049057(CHEMBL3319505 | US10730833, Compound 10d | US99696...)
Affinity DataEC50:  86nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049057(CHEMBL3319505 | US10730833, Compound 10d | US99696...)
Affinity DataEC50:  86nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails US Patent