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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50460783'
TargetAurora kinase B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50460783(CHEMBL4229135)
Affinity DataIC50: <13nMAssay Description:Inhibition of Aurora B (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50460783(CHEMBL4229135)
Affinity DataEC50:  203nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed