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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'BRD9 (aa 134-239)' and Ligand = 'BDBM321388'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
BRD9 (aa 134-239)


(Homo sapiens (human))
BDBM321388
PNG
(3-(6-butyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-...)
Show SMILES CCCCn1cc(-c2cc(ccc2OC)C#N)c2cc[nH]c2c1=O
Show InChI InChI=1S/C19H19N3O2/c1-3-4-9-22-12-16(14-7-8-21-18(14)19(22)23)15-10-13(11-20)5-6-17(15)24-2/h5-8,10,12,21H,3-4,9H2,1-2H3
PDB

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 46n/an/an/an/an/an/a



GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...


US Patent US10183009 (2019)

More data for this
Ligand-Target Pair