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Found 2 Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM31375'
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM31375(CHEMBL28504 | terephthalamide scaffold, 23)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity for Bcl-xL was assessed by a fluorescence polarizationassay using a fluorescently labeled 16-mer Bak-peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM31375(CHEMBL28504 | terephthalamide scaffold, 23)
Affinity DataKi:  1.10E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Fluorescence polarization experiments were conducted on a Photon Technology International instrument using a 0.3 cm path length cuvette. Spectra were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed