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Found 8 Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor' and Ligand = 'BDBM25756'
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Mus musculus)
Friedrich-Alexander Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]CGP12177 from mouse beta1 adrenoceptor expressed in HEK293T cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]CGP12177 from human beta1 adrenoceptor expressed in HEK293T cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
Niigata College Of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataKi:  63.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataIC50:  190nMAssay Description:Tested for beta1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-1 adrenergic receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataIC50:  320nMAssay Description:Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o...More data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataKd:  55nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-1 adrenergic receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)
Affinity DataKd:  15nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed