Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with Target = 'Beta-2 adrenergic receptor' and Ligand = 'BDBM50213120'
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataKi:  1.93E+3nM ΔG°:  -30.3kJ/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataKi:  1.95E+3nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataKi:  1.93E+6nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataIC50:  2.01nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR, 1321N1 or U87MG cells were seeded in a 96-well plate at approximately 5,000 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataKd:  1.95E+3nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataKd:  1.95E+3nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50213120((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Affinity DataEC50:  506nMAssay Description:Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed