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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 1' and Ligand = 'BDBM284005'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-adrenergic receptor kinase 1


(Homo sapiens (Human))
BDBM284005
PNG
(E31 | US10023564, Example 31)
Show SMILES CC1=C(C(NC(=O)N1)c1ccc(F)c(CC(=O)N2CCOC(CCO)C2)c1)C(=O)Nc1ccc2[nH]ncc2c1
Show InChI InChI=1S/C27H29FN6O5/c1-15-24(26(37)31-19-3-5-22-18(11-19)13-29-33-22)25(32-27(38)30-15)16-2-4-21(28)17(10-16)12-23(36)34-7-9-39-20(14-34)6-8-35/h2-5,10-11,13,20,25,35H,6-9,12,14H2,1H3,(H,29,33)(H,31,37)(H2,30,32,38)
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.50E+3n/an/an/an/a7.0n/a



THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent


Assay Description
GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...


US Patent US10023564 (2018)

More data for this
Ligand-Target Pair