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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 1' and Ligand = 'BDBM284008'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-adrenergic receptor kinase 1


(Homo sapiens (Human))
BDBM284008
PNG
(E34 | US10023564, Example 34)
Show SMILES CN(Cc1nc(C)c[nH]1)C(=O)Cc1cc(ccc1F)C1NC(=O)NC(C)=C1C(=O)Nc1ccc2[nH]ncc2c1
Show InChI InChI=1S/C27H27FN8O3/c1-14-11-29-22(31-14)13-36(3)23(37)10-17-8-16(4-6-20(17)28)25-24(15(2)32-27(39)34-25)26(38)33-19-5-7-21-18(9-19)12-30-35-21/h4-9,11-12,25H,10,13H2,1-3H3,(H,29,31)(H,30,35)(H,33,38)(H2,32,34,39)
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.20E+3n/an/an/an/a7.0n/a



THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent


Assay Description
GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...


US Patent US10023564 (2018)

More data for this
Ligand-Target Pair