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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 1' and Ligand = 'BDBM284010'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-adrenergic receptor kinase 1


(Homo sapiens (Human))
BDBM284010
PNG
(E36 | US10023564, Example 36)
Show SMILES CC(C)CN(CC#C)C(=O)Cc1cc(ccc1F)C1NC(=O)NC(C)=C1C(=O)Nc1ccc2[nH]ncc2c1
Show InChI InChI=1S/C28H29FN6O3/c1-5-10-35(15-16(2)3)24(36)13-19-11-18(6-8-22(19)29)26-25(17(4)31-28(38)33-26)27(37)32-21-7-9-23-20(12-21)14-30-34-23/h1,6-9,11-12,14,16,26H,10,13,15H2,2-4H3,(H,30,34)(H,32,37)(H2,31,33,38)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.60E+3n/an/an/an/a7.0n/a



THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent


Assay Description
GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...


US Patent US10023564 (2018)

More data for this
Ligand-Target Pair