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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 1' and Ligand = 'BDBM50444104'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-adrenergic receptor kinase 1


(Homo sapiens (Human))
BDBM50444104
PNG
(CHEMBL3093247)
Show SMILES Nc1ncc(cc1-c1nc2ccc(NC(=O)c3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C27H24FN7O2/c28-19-3-1-16(2-4-19)26(36)33-20-5-6-23-24(12-20)37-27(34-23)22-11-17(13-31-25(22)29)18-14-32-35(15-18)21-7-9-30-10-8-21/h1-6,11-15,21,30H,7-10H2,(H2,29,31)(H,33,36)
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Similars

Article
PubMed
n/an/a 960n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of GRK-2 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...


Bioorg Med Chem Lett 23: 6711-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.10.036
BindingDB Entry DOI: 10.7270/Q2SX6FPP
More data for this
Ligand-Target Pair