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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 1' and Ligand = 'BDBM50444137'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-adrenergic receptor kinase 1


(Homo sapiens (Human))
BDBM50444137
PNG
(CHEMBL3093258)
Show SMILES Nc1ncc(cc1-c1nc2cc(ccc2o1)N1CCCCC1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C25H29N7O/c26-24-21(12-17(14-28-24)18-15-29-32(16-18)19-6-8-27-9-7-19)25-30-22-13-20(4-5-23(22)33-25)31-10-2-1-3-11-31/h4-5,12-16,19,27H,1-3,6-11H2,(H2,26,28)
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MMDB

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Similars

Article
PubMed
n/an/a 850n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of GRK-2 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...


Bioorg Med Chem Lett 23: 6711-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.10.036
BindingDB Entry DOI: 10.7270/Q2SX6FPP
More data for this
Ligand-Target Pair