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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM102963'
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102963(US8541427, 34)
Affinity DataKi:  5.60nM ΔG°:  -47.9kJ/mole IC50:  86nMT: 2°CAssay Description:A homogeneous time-resolved FRET assay was used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. The assay monit...More data for this Ligand-Target Pair
In DepthDetails US Patent