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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM156249'
Target
Beta-secretase 1
(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Ligand
BDBM156249
(US9018391, 11)
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Affinity Data
IC50: 14.6nM
pH: 4.4
Assay Description:
The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...
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Target Info
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antibodypedia
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Ligand Info
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US Patent
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