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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM16730'
TargetBeta-secretase 1(Homo sapiens (Human))
Applied Science University

Curated by ChEMBL
LigandPNGBDBM16730(N-{2-[4-(2-hydroxyethyl)piperazin-1-yl]-5-phenylph...)
Affinity DataIC50:  110nMAssay Description:Inhibition of BACE1 after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Applied Science University

Curated by ChEMBL
LigandPNGBDBM16730(N-{2-[4-(2-hydroxyethyl)piperazin-1-yl]-5-phenylph...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed