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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM247292'
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM247292(US9447085, 8)
Affinity DataKi:  9nM ΔG°:  -46.7kJ/molepH: 5.0 T: 2°CAssay Description:This assay monitors the increase of 620 nm fluorescence that resulted from BACE1 cleavage of an APPswedish APPswe mutant peptide FRET substrate (QSY7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent