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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM258273'
TargetBeta-secretase 1(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM258273(US9493485, 8-109)
Affinity DataIC50:  68nMpH: 7.0Assay Description:BACE1 activity can be assessed in an AlphaScreenŽ assay. Compounds to be assessed (e.g. compounds as described in the above examples) are serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM258273(US9493485, 8-109)
Affinity DataIC50:  1.16E+3nMpH: 4.5 T: 2°CAssay Description:Compounds are also assessed for BACE1 and Cathepsin D activity using an FP Assay. Compounds to be assessed (e.g. compounds as described in the above ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent