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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM291121'
Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM291121
(US9580396, Example 2m)
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Affinity Data
Ki: 303nM
pH: 5.0
Assay Description:
A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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Ligand Info
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Details
US Patent
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