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Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM335469'
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM335469((3R,6S)-5-amino-3-(2-((2-(but- 2-yn-1-yloxy)pyrido...)
Affinity DataKi:  1.5nMAssay Description:The compounds of the invention were determined to be potent inhibitors of BACE-1 using the following assay.The following reagents were used in this a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent