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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM404167'
Target
Beta-secretase 1
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM404167
(US10336717, Compound 467)
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Affinity Data
IC50: 2.80nM
Assay Description:
For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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Details
US Patent
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