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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM50271166'
TargetBeta-secretase 2(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50271166(CHEMBL4130055)
Affinity DataKi:  6nMAssay Description:Binding affinity to human autoBACE2 using QSY7-APPswe-Eu as substrate preincubated for 30 mins followed by substrate addition measured after 90 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50271166(CHEMBL4130055)
Affinity DataKi:  6nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent