Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50258558'
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258558((S)-3-(4-((5-sec-butyl-3-(2,6-dichlorophenyl)isoxa...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258558((S)-3-(4-((5-sec-butyl-3-(2,6-dichlorophenyl)isoxa...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed