BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bradykinin-1 Receptor' and Ligand = 'BDBM107153'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107153
PNG
(US8592426, 2)
Show SMILES FC(F)COc1c(Cl)cc(Cl)cc1-c1ccc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C23H19Cl2F5N2O3/c24-13-8-15(19(16(25)9-13)35-10-18(26)27)12-1-3-14-11(7-12)2-4-17(14)31-20(33)22(5-6-22)32-21(34)23(28,29)30/h1,3,7-9,17-18H,2,4-6,10H2,(H,31,33)(H,32,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
146n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107153
PNG
(US8592426, 2)
Show SMILES FC(F)COc1c(Cl)cc(Cl)cc1-c1ccc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C23H19Cl2F5N2O3/c24-13-8-15(19(16(25)9-13)35-10-18(26)27)12-1-3-14-11(7-12)2-4-17(14)31-20(33)22(5-6-22)32-21(34)23(28,29)30/h1,3,7-9,17-18H,2,4-6,10H2,(H,31,33)(H,32,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 76.8n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair