BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bradykinin-1 Receptor' and Ligand = 'BDBM107175'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107175
PNG
(US8592426, 24)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(N)CC1
Show InChI InChI=1S/C22H20ClFN4O2/c1-11-26-20(28-30-11)19-16(9-14(23)10-17(19)24)13-2-4-15-12(8-13)3-5-18(15)27-21(29)22(25)6-7-22/h2,4,8-10,18H,3,5-7,25H2,1H3,(H,27,29)/t18-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
36.4n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


Citation and Details
More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107175
PNG
(US8592426, 24)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(N)CC1
Show InChI InChI=1S/C22H20ClFN4O2/c1-11-26-20(28-30-11)19-16(9-14(23)10-17(19)24)13-2-4-15-12(8-13)3-5-18(15)27-21(29)22(25)6-7-22/h2,4,8-10,18H,3,5-7,25H2,1H3,(H,27,29)/t18-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


Citation and Details
More data for this
Ligand-Target Pair