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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bradykinin-1 Receptor' and Ligand = 'BDBM107185'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107185
PNG
(US8592426, 34)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1cc2CCC(NC(=O)C3(CC3)NC(=O)c3ccnnc3)c2c(F)c1
Show InChI InChI=1S/C27H21ClF2N6O3/c1-13-33-24(36-39-13)23-18(10-17(28)11-20(23)30)16-8-14-2-3-21(22(14)19(29)9-16)34-26(38)27(5-6-27)35-25(37)15-4-7-31-32-12-15/h4,7-12,21H,2-3,5-6H2,1H3,(H,34,38)(H,35,37)
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KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
15.1n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107185
PNG
(US8592426, 34)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1cc2CCC(NC(=O)C3(CC3)NC(=O)c3ccnnc3)c2c(F)c1
Show InChI InChI=1S/C27H21ClF2N6O3/c1-13-33-24(36-39-13)23-18(10-17(28)11-20(23)30)16-8-14-2-3-21(22(14)19(29)9-16)34-26(38)27(5-6-27)35-25(37)15-4-7-31-32-12-15/h4,7-12,21H,2-3,5-6H2,1H3,(H,34,38)(H,35,37)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 0.600n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair