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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1)' and Ligand = 'BDBM313801'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1)


(Homo sapiens (Human))
BDBM313801
PNG
(US10167292, Example 45)
Show SMILES Cc1nnn2CCN(c3ccc(Cl)cc3)c3cc(ccc3-c12)C(=O)NOCCO
Show InChI InChI=1S/C20H20ClN5O3/c1-13-19-17-7-2-14(20(28)23-29-11-10-27)12-18(17)25(8-9-26(19)24-22-13)16-5-3-15(21)4-6-16/h2-7,12,27H,8-11H2,1H3,(H,23,28)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Catalyst Therapeutics Pty Ltd.

US Patent


Assay Description
BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...


US Patent US10167292 (2019)

More data for this
Ligand-Target Pair