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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1)' and Ligand = 'BDBM313805'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1)


(Homo sapiens (Human))
BDBM313805
PNG
(US10167292, Example 49)
Show SMILES Cc1nnn2CCN(c3ccc(Cl)cc3)c3cc(ccc3-c12)-c1noc(=O)[nH]1
Show InChI InChI=1S/C19H15ClN6O2/c1-11-17-15-7-2-12(18-21-19(27)28-23-18)10-16(15)25(8-9-26(17)24-22-11)14-5-3-13(20)4-6-14/h2-7,10H,8-9H2,1H3,(H,21,23,27)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Catalyst Therapeutics Pty Ltd.

US Patent


Assay Description
BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...


US Patent US10167292 (2019)

More data for this
Ligand-Target Pair