BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2)' and Ligand = 'BDBM179460'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2)


(Homo sapiens (Human))
BDBM179460
PNG
(US9675697, Cpd. No. 17)
Show SMILES COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(-c3c[nH]c4ccccc34)c21
Show InChI InChI=1S/C25H20N4O2/c1-13-23(14(2)31-29-13)17-10-21-16(11-22(17)30-3)24-20(28-21)8-9-26-25(24)18-12-27-19-7-5-4-6-15(18)19/h4-12,27-28H,1-3H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<10<-45.7 142n/an/an/an/a7.525



THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent


Assay Description
The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...


US Patent US9675697 (2017)


BindingDB Entry DOI: 10.7270/Q2CC0XV6
More data for this
Ligand-Target Pair