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Found 8 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 3' and Ligand = 'BDBM50365264'
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  28.4nMAssay Description:Displacement of acetylated histone peptide from BRD3-BD1,2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  28.4nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd3 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  220nMAssay Description:Inhibition of His6-tagged BRD3 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGSK-bio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  350nMAssay Description:Inhibition of His6-tagged BRD3 expressed in Escherichia coli after 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataIC50:  631nMAssay Description:Binding affinity to His6-tagged BRD3 (unknown origin) after 60 mins by fluorescence anisotropy binding AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataKd:  19nMAssay Description:Binding affinity to His6-tagged BRD3 expressed in Escherichia coli by isothermal colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataKd:  19nMAssay Description:Binding affinity to N-terminal portion of human Brd3 containing bromodomain BD12 expressed in Escherichia coli by isothermal titration calorimetric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Japan Science And Technology Agency

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)
Affinity DataKd:  46nMAssay Description:Binding affinity to BRD3-BD1,2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed