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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM140199'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM140199
PNG
(US8906911, 8)
Show SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1[C@H]2CC[C@@H]1CN(C2)c1cc(ccn1)C(F)(F)F
Show InChI InChI=1S/C27H37F3N4O3/c1-36-23-16-37-10-7-22(23)32-19-11-17-3-2-8-26(17,13-19)25(35)34-20-4-5-21(34)15-33(14-20)24-12-18(6-9-31-24)27(28,29)30/h6,9,12,17,19-23,32H,2-5,7-8,10-11,13-16H2,1H3/t17-,19-,20-,21+,22+,23-,26-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.44E+4n/an/an/an/a7.44



AbbVie Inc.

US Patent


Assay Description
Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha┬▒16 coupling protein. All compounds were dissolved in DMSO a...


US Patent US8906911 (2014)


BindingDB Entry DOI: 10.7270/Q2BV7FBV
More data for this
Ligand-Target Pair