Found 5 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50212128'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.04nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair