Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50258046'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at CCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  259nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)
Affinity DataIC50:  259nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed