Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50315993'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as reduction of chemotaxis in presence of 0.1 M BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 45 mins in presence of 0.1 M bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]-MCP1 from CCR2 in human THP1 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50315993(CHEMBL1091605 | N-((S)-1-((1S,2R,4R)-4-(isopropyl(...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]-labeled human MCP1 from CCR2 in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed