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Found 5 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50234723'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50234723((2,4-dimethyl-1-oxy-pyridin-3-yl)-[4'-methyl-4-(ph...)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [125I]RANTES from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Macaca fascicularis)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50234723((2,4-dimethyl-1-oxy-pyridin-3-yl)-[4'-methyl-4-(ph...)
Affinity DataIC50:  8.10nMAssay Description:Displacement of radiolabeled MIP-1alpha from cynomolgus monkey CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50234723((2,4-dimethyl-1-oxy-pyridin-3-yl)-[4'-methyl-4-(ph...)
Affinity DataIC50:  16.2nMAssay Description:Antagonist activity at human CCR5 expressed in L1.2 cells assessed as MIP-1-alpha-induced Ca2+ mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50234723((2,4-dimethyl-1-oxy-pyridin-3-yl)-[4'-methyl-4-(ph...)
Affinity DataIC50:  43.6nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as MIP-1-alpha-induced Ca2+ mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Macaca fascicularis)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50234723((2,4-dimethyl-1-oxy-pyridin-3-yl)-[4'-methyl-4-(ph...)
Affinity DataIC50:  64nMAssay Description:Antagonist activity at cynomolgus monkey CCR5 expressed in CHO cells assessed as MIP-1-alpha-induced Ca2+ mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed