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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-RAF (Y340D Y341D)' and Ligand = 'BDBM322525'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-RAF (Y340D Y341D)


(Homo sapiens (Human))
BDBM322525
PNG
(5-[3[4-(4-pyridyl)-1H-imidazol-2-yl]chroman-6-yl]o...)
Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccncc3)ccnc2N1
Show InChI InChI=1S/C25H21N5O3/c31-23-4-2-19-22(7-10-27-25(19)30-23)33-18-1-3-21-16(12-18)11-17(14-32-21)24-28-13-20(29-24)15-5-8-26-9-6-15/h1,3,5-10,12-13,17H,2,4,11,14H2,(H,28,29)(H,27,30,31)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<4n/an/an/an/an/an/a



Redx Pharma PLC

US Patent




US Patent US10183939 (2019)

More data for this
Ligand-Target Pair