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Found 4 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 2' and Ligand = 'BDBM150824'
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM150824(US8981106, 14 (SX-585) | USRE47267, Compound 14)
Affinity DataIC50:  28nMT: 2°CAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM150824(US8981106, 14 (SX-585) | USRE47267, Compound 14)
Affinity DataIC50:  28nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM150824(US8981106, 14 (SX-585) | USRE47267, Compound 14)
Affinity DataIC50:  1.06E+3nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM150824(US8981106, 14 (SX-585) | USRE47267, Compound 14)
Affinity DataEC50:  1.81E+3nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
In DepthDetails US Patent