Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 2' and Ligand = 'BDBM50236296'
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50236296(1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50236296(1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...)
Affinity DataIC50:  250nMAssay Description:Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Oryctolagus cuniculus)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50236296(1-(2-(5-bromo-2-(4-fluorophenyl)-1H-indol-3-yl)eth...)
Affinity DataIC50:  5.80E+3nMAssay Description:Antagonist activity at rabbit CXCR2 by neutrophil chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed