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Found 1 hit Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor (C5aR)' and Ligand = 'BDBM50251636'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))
BDBM50251636
PNG
((+/-)-2-(2,6-dimethylphenyl)-4-methoxy-N-(3-methox...)
Show SMILES COc1cccc(N(C)C2CCCc3nc(cc(OC)c23)-c2c(C)cccc2C)c1C
Show InChI InChI=1/C27H32N2O2/c1-17-10-7-11-18(2)26(17)21-16-25(31-6)27-20(28-21)12-8-14-23(27)29(4)22-13-9-15-24(30-5)19(22)3/h7,9-11,13,15-16,23H,8,12,14H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 18: 3852-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.059
BindingDB Entry DOI: 10.7270/Q2765F4X
More data for this
Ligand-Target Pair