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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM345456'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CREB-binding protein


(Homo sapiens (Human))
BDBM345456
PNG
(Propane-2-sulfonic acid [2-(2,5-dichloro-phenoxy)-...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2cc(Cl)ccc2Cl)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C20H20Cl2N4O4S/c1-11(2)31(28,29)25-18-9-16(13-7-12(3)19(27)26(4)10-13)23-20(24-18)30-17-8-14(21)5-6-15(17)22/h5-11H,1-4H3,(H,23,24,25)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)

More data for this
Ligand-Target Pair